Evaluation of the phytochemical content, in vitro antioxidant. Their structures were determined by physical and spectroscopical one dimensional 1d and 2dnmr analysis, including heteronuclear multiple bond correlation and. The powdered fruit was stored in an air tight bottle until used. However, there is no documented report to the best of the researchers knowledge on the antidiabetic and specifically on the antihyperlipidemic effect of the seed extract of d. Pdf effect of methanolic extract of dennettia tripetala. A tree of the rainforest and occasionally in the savanna, to 18 m high by 60 cm girth, of limited distribution in ivory coast, s nigeria and w cameroons. Fifteen 15 male albino wistar rats weighing between 150 200g were used for the study and randomly assigned into three study groups of. This tree flourishes at the onset of rain, from april to june 2 the fruits of the tree are edible and have a peppery and spicy taste. Ripe fruits of dennettia tripetala were analysed for proximate composition, and mineral and vitamin contents. Antimicrobial potential of toothpaste formulated from.
Therefore, the study was designed to investigate the hypoglycemic, antihyperlipidemic, and. The effects of methanol extract of dennettia tripetala. Here are the 18 wondrous benefits of pepper fruit dennettia tripetala you definitely need to know. It is also known as ako, mmimi, or ata igbere by the edo. The plant is a tropical african plant and the fruits are commonly eaten as spices and consumed as a stimulant, and its various parts are used in the treatment of fever, cough and as antiemetics. Dennettia tripetala is commonly known as pepper fruit by the. The effects of methanol extract of dennettia tripetala mmimi. The fruits, green at first then turning red, ripen in april. Antinociceptive and antiinflammatory effects of essential. The effect of ethanol extract of dennettia tripetala pepper. Aqueous extract of dennettia tripetala ameliorates liver and. Dennettia tripetala commonly known as pepperfruit is widely consumed by the inhabitants of west africa due to its distinctive spicy taste. Dennettia tripetala are applied to the food meant for pregnant women and are important in the diets of postpartum women, during which time it is claimed that spices and herbs aid uterine contraction okwu and morah, 2004. Home list of science lab technology project topics and materials pdf the effects of methanol extract of dennettia tripetala mmimi on the liver marker enzymes.
Based on this fact, this study examined the macropropagation of dennettia tripetala in order to domesticate and ensure its continuous availability for human utilization. The presence of antioxidants such as flavonoids and ascorbic acid in d. Feb 04, 2019 the various chemical components found in dennettia tripetala are the followings, 2methylbenzyl alcohol, eugenol, nerolidol and 9octadecenoic acid oleic acid while, 2methylbenzyl alcohol, eugenol, caryophyllene, 1, 5dimethyl1vinyl4hexenyl butyrate, 1methyltricyclo 2. The median lethal dose ld 50 was estimated using revised up and down procedure. The study was designed to investigate the ameliorative effect of methanolic extract of dennettia tripetala dt on oxidative stress and blood glucose level in type ii diabetic male wistar rats. It is a tropical small tree that abounds throughout the rainforest zone of africa. Alkaline phosphatase alp, aspartate aminotransferase ast and alanine aminotransferasealt in the serum of albino rats was investigated.
Dennettia tripetala, an important medicinal and sociocultural fruit crop in nigeria has germination and early growth problems. Dataset gbif backbone taxonomy rank species published in a. Extraction and isolation ripe fruits of dennettia tripetala were obtained from the bush, washed to be free from debris and sundried for two days and later dried with astell hearson oven at a temperature range of 45c50c. It is capable of protecting the liver and kidney of rats from damage when administered prior to a single exposure of carbon tetrachloride. The rats in this group were orogastrically given 1 ml equivalent to 300 mgkg body weight of stem dennettia tripetala extract daily for 21 days. Dennettia tripetala extract was able to prevent this and boost both the structural and functional integrity of the liver, including its synthetic capacity. The study revealed the safety of dennettia tripetala seed on man and the environment. The study was conducted under ambient conditions of 250c 280c and 65% 75% relative humidity in the laboratory for a period of 3 months. Pdf chromone and phenanthrene alkaloids from dennettia.
The aim of this study was to document the possible ameliorative effect of the aqueous extract of dennettia tripetala fruits on rats subjected to multiple exposures of. Thereafter 300g of the homogenized sample was extracted with ethanol. Urea and creatinine are commonly used as markers of kidney function. Baker annonaceae, or pepper fruit tree, is a wellknown nigerian spicy medicinal plant. Preexposure to dennettia tripetala ethanolic fruit extract. Aqueous extract of dennettia tripetala ameliorates liver. The highly nutritious fruit is rich in protein, carbohydrates, as well as the antioxidant vitamins a, c, and e. Effect of ethanolic extract of dennettia tripetala fruit. Dennettia tripetala pepper fruit tree of the family annonaceae is used as a spice and condiment in west africa. Pdf macropropagation of dennettia tripetala baker f. The hypoglycemic activity in crude methanol seed extract of dt cmedt and methanol seed fraction of dt mfdt measured by glucose oxidase method was increased by 47. Pdf isolation and characterization of phenanthrenic.
The effect of oral administration of ethanolic extract of dennettia tripetala fruits on haematological parameters in albino wistar rats was investigated. Dennettia tripetala dt is consumed in west africa as a spice. The effects of methanol extract of dennettia tripetala mmimi on the liver marker enzymes ast, alt and alp of albino rats home list of science lab technology project topics and materials pdf the effects of methanol extract of dennettia tripetala mmimi on the liver marker enzymes ast, alt and alp of albino rats. It is also used in traditional medicine for treating cough, fever and other ailments. Chemical composition of the eos and identity of constituents are presented in table 1. Here are the 18 wondrous benefits of pepper fruit dennettia tripetala you definitely need to. Aqueous extract of dennettia tripetala ameliorates liver and kidney damage caused by multiple exposures to carbon tetrachloride sylvia o. Aqueous extract of dennettia tripetala ameliorates. Essential oil obtained from the fruit in clevenger modified apparatus, was characterized by high resolution gcms, while antioxidant and. The mineral, vitamin and nutrient composition of the fruit of dennettia tripetala were determined. This study set out to investigate fruit ripeness status and. Dennettia tripetala pepper fruit is believed to be endowed with hypoglycemic potentials. Preexposure to dennettia tripetala ethanolic fruit.
Our work showed that dennettia tripetala contained crude protein 15. Its fruits have been shown to possess phytochemicals with proven antioxidant capabilities. Uvariopsis tripetala is a species of plant in the annonaceae family. In this study we evaluated the analgesic and anti inflammatory activities of the essential oil eo of the fruits ofdennettia tripetala in rodents. Nutritional benefits okwu and morah 2004 study shows that dennettia tripetala contains 0.
The young leaves are chewed on account of their pungent spicy taste. Memory enhancing, anticholinesterase and antimicrobial activities of. This study was designed to investigate the antisickling properties of aqueous leaf extracts of physalis. Dennettia tripetala pepper fruit tree of the family annonaceae is used. It is also used traditionally as a remedy for cough. The effect of ethanol extract of dennettia tripetala. Bactericidal and antioxidant properties of essential oils. Dt roots elicit in vitro antioxidant capabilities similar to that of ascorbic acid. Antinociceptive and antiinflammatory effects of essential oil. Some quantities of dennettia tripetala fruits were air dried for one week and then pulverized by grinding using pestle and mortar.
Dennettia tripetala pepper fruit belongs to the annonaceae family etukudo 2000. Antisickling properties of aqueous extracts of dennettia. In this study, we evaluated the potency of the ethanol extract of dt. Dennettia tripetala powder and reduced rates of pirimiphosmethyl dust were tested on cowpea against c. When the levels of these metabolites increase in serum, it indicates that there is a problem with the kidney 26, 30. Sickle cell disease scd is a group of genetically inherited blood disorders typically passed from the parent to the offspring and is characterized by an abnormality and a reduction in the oxygen carrying capacity of the haemoglobin molecule of erythrocytes. Therefore, the study was designed to investigate the hypoglycemic, antihyperlipidemic. Dennettine, a new 2,6dimethoxychromone and three known phenanthrene alkaloids uvariopsine, stephenanthrine and argentinine in addition to the phenolic and known compound vanillin were isolated from the roots of dennettia tripetala. It is widely grown in the west african rainforest region including the south east and south west nigeria.
Effect of ethanolic extract of dennettia tripetala fruit on. Toxicological and histopathological effects of dennettia. Lethality studies revealed that the extract had an ld50 value of 251. Essential oil constituents including carvacrol, carvone, caryophyllene, limonene and thymol have been reported to possess these properties 7, 11, 12. The effect of ethanol extract of dennettia tripetala pepper fruit on gastric acid secretion in wistar rats bright e 1, mfem c 2, ugumanim a 1 and ukpong m 1. Nov 19, 2018 dennettia tripetala or pepperfruit is a medicinal plant that grows in nigeria and some parts of west africa. They also had free access to normal rat chow and water adlibitum. In this study we evaluated the analgesic and anti inflammatory activities of the essential oil eo of the fruits of dennettia tripetala in rodents. The aim of this study was to document the possible ameliorative effect of the aqueous extract of dennettia tripetala fruits on rats subjected to multiple exposures of carbon. Alkaline phosphatase alp, aspartate aminotransferase ast and alanine aminotransferasealt in the serum of albino. Mineral and nutritive value of dennettia tripetala fruits.
Investigation into hypoglycemic, antihyperlipidemic, and. Uvariopsis tripetala name homonyms dennettia tripetala baker f. Dennettia tripetala is a medicinal plant with in vitro antioxidant activities. Type ii diabetes was induced by a single intraperitoneal injection of streptozotocin 40 mgkg after 2 weeks of 10% fructose diet. Consequently, there is a great pressure on the seed, which is the only alternative for its inexpensive propagation. The wood is white, soft and not durable, and is susceptible to termites.
Baker annonaceae also known as pepperfruit tree is a woody plant of at least 3meters height with simple leaves and abundant fruits widely consumed in southern nigeria. This study investigated the hypoglycemic, antihyperlipidemic, and renoprotective potentials of dennettia tripetala dt in a rat model of diabetes. The effects of methanol extract of dennettia tripetala mmimi on the liver marker enzymes ast, alt and alp of albino rats. It is also used traditionally as a remedy for cough, fever, toothache, diabetes, and nausea. The leaves and the seeds are used in folk medicine for the treatment of fever, cough, asthma, catarrh, diarrhea and rheumatism burkill 1985. Research article effect of ethanol extract of ripe fruits. Nov 28, 2016 the antibacterial and antioxidant properties of the essential oils eos of unripe and ripe fruits of dennettia tripetala and their potential for the management of infectious and oxidativestress diseases were investigated invitro in this study. I s s n 1 8 4 7 6 4 8 1 e i s s n 1 8 4 9 0 8 9 1 original scientific paper alfred ossai onefeli 1, adejoke olukemi akinyele 1 background and purpose. Memory enhancing, anticholinesterase and antimicrobial. The effect of oral administration of methanol extract of dennettia tripetala on the activity of liver marker enzymes. Hence, the species has been rendered threatened in the forest. African journal of biotechnology effect of methanolic. Effect of dennettia tripetala powder and reduced rates of. Dennettia tripetala or pepperfruit is a medicinal plant that grows in nigeria and some parts of west africa.
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